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Epideomiological Study on Leukaemia
54,90 € *
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Leukaemia is commonly known as blood cancer with fatal characteristics. The age standardize rate of cancer in India is 60 to 90%. Epidemiology played an imperative role to understand the causes of diseases and its geographical prevalence which provides the opportunity to draft the policy and treatment strategies. In this book, an attempt is made to identify an epidemiological characteristic of leukemia patients of Gujarat state. This is the endeavor to describe the age-specific occurrence, deviation of hematological and biochemical parameter and genetic mutation of four main types of leukaemia (Chronic myeloid leukaemia CML, Chronic lymphoid leukaemia, CLL, Acute lymphoid leukaemia, ALL and Acute myeloid leukaemia, AML).

Anbieter: Dodax
Stand: 04.12.2020
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Advances in Chronic Lymphocytic Leukemia
181,89 € *
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Chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western world. CLL has a highly varied clinical course. While advances in CLL therapy are noted, many patients still succumb to this illness. Like most progress in medicine, solid advances in the diagnosis, prognosis and treatment of CLL are rooted in an in-depth understanding of the basic and translational biology of CLL. In this book, CLL experts have contributed state-of-the-art summaries of various important aspects of CLL biology and have discussed the translational implication of such findings. This book, which is directed at physicians and researchers alike, aims to educate broadly and deeply. Intentionally, the many aspects and nuances of CLL clinical care that can only really be appreciated through direct patient care are not covered here, but instead, the book presents basic aspects of CLL that underlie many of the contemporary decisions that are made in CLL research and clinical settings.We hope that this book will critically inform the community and stimulate interest in CLL, which will ultimately translate into better CLL research, prognostication and therapy, with the end goal of providing a better outlook for patients afflicted with this common leukemia.

Anbieter: Dodax
Stand: 04.12.2020
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Flow Cytometric Immunophenotyping of Mature B-c...
64,90 € *
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Flow cytometer became one of the most pivotal and definitive techniques in the diagnosis and classification of mature B cell neoplasm (MBCN). Since flow cytometer exploits the laser and photomultiplier technology for reliable high quality result with extremely high sensitivity and specificity, we used these important specifications in this project to study the properties of B cells in the adult patients whose have initial diagnosis of (MBCN). This book discussed the diversity of the flow cytometer parameters (such as the percentage of positive cells, the mean fluorescence intensity and the positive peak width) which showed a remarkable role in the diagnosis of MBCN and in differentiation between CLL and NHL. The worth of the idea of this diversity of the parameters exhibited in the minimization of the markers number following into the minimization of panel cost without affecting the result. Also, using of CD20 & CD19 with their flow cytometric parameters and without the other scoring markers showed a significant role in differentiation between CLL and NHL. These ideas are appropriate for the used in laboratories of limited resources.

Anbieter: Dodax
Stand: 04.12.2020
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Chronic Lymphocytic Leukemia
80,94 € *
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This book summarizes current knowledge on chronic lymphocytic leukemia (CLL), taking into account the most recent research. All aspects are considered, including pathophysiology, clinical presentation, diagnosis, prognosis, treatment, follow-up, and complications and their management. Readers will find important information on the various prognostic markers as well as practical guidance on the use of different diagnostic procedures. A key focus of the book is the changing treatment paradigm in CLL as progress in understanding of pathogenesis and pathophysiology leads to the identification of new potential therapeutic targets. General treatment concepts are clearly described, and it is explained how choice of treatment for CLL depends on stage, age, and performance status as well as specific genetic aberrations. In addition, frontline therapeutic strategies for disease relapse, including allogeneic stem cell transplantation, are reported. Looking beyond CLL, the diagnosis and therapy of T-cell prolymphocytic leukemia and T-cell large granular lymphocyte leukemia, two rare CLL-related entities, are addressed.  

Anbieter: Dodax
Stand: 04.12.2020
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Chronic Lymphocytic Leukemia
59,90 € *
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Chronic lymphocytic leukemia (CLL) is the most common hematological malignancy in western countries. It is characterized by the accumulation of monoclonal CD5+ B-lymphocytes in blood, bone marrow, and lymphoid organs, due to an imbalance between proliferation and cell death. It is a complex disease that remains misunderstood. This book, therefore describes globally this very common but extremely complex type of leukemia. Throughout this book the principal biological hallmarks of B-cells are compared with the principal features of CLL-leukemic B-cells. Additionally the current CLL epidemiology is indicated and the most common methods of diagnosis are discussed. Moreover, the principal prognostic factors of CLL are described, passing from a medical point of view to a biological description. The major characteristics conferring apoptotic avoidance of CLL cells and proliferation factors are detailed, such as the principal models for its in vitro and in vivo study. Finally, the leading conventional treatments and new therapeutic strategies against CLL are listed with their principal biological targets.

Anbieter: Dodax
Stand: 04.12.2020
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Married With Cancer
24,90 CHF *
zzgl. 3,50 CHF Versand

Eileen and Jimmy Newell had been married 24 years when Jimmy was diagnosed with Chronic Lymphocytic Cancer (CLL) during a routine physical exam. From the moment he called Eileen to deliver the news, she went from wife to wife/caregiver, a challenging role even with her training as a nurse. After several rounds of chemo over the course of seven years, Jimmy's cancer was declared as in remission, and things were looking up. Life was good-until Eileen was diagnosed with breast cancer ten years later, and suddenly, everything was turned on its head. Jimmy had to step into the role of caregiver, a role that life and a career in higher education had not prepared him for. In their book Married With Cancer, Eileen and Jimmy share how they coped as a couple through their cancer diagnoses and treatments, as patient and as caregiver. It hasn't been an easy journey, but they've had boundless love and laughter, some tears, and a few life lessons, which they share in this book to give hope and encouragement to their readers as they make their own journey toward survival.

Anbieter: Orell Fuessli CH
Stand: 04.12.2020
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ZAP-70 phosphorylation and other prognostic fac...
103,00 CHF *
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This book is the culmination of a major three and half-years' work on B-chronic lymphocytic leukaemia (B-CLL) to stratify its prognostication. It represents a comprehensive analysis of various prognostic factors in adult B-CLL patients. The book is a fantastic resource and could be used by a range of professionals. Its main focus is on the laboratory diagnosis of B-CLL using basic methods as well as flow cytometry. Flow cytometry is further employed to demonstrate that ZAP-70 positive cells are more responsive to signals derived from their surounding environment, such as stromal cell-derived factor 1-alpha (SDF-1a).

Anbieter: Orell Fuessli CH
Stand: 04.12.2020
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ZAP-70 phosphorylation and other prognostic fac...
53,99 € *
ggf. zzgl. Versand

This book is the culmination of a major three and half-years' work on B-chronic lymphocytic leukaemia (B-CLL) to stratify its prognostication. It represents a comprehensive analysis of various prognostic factors in adult B-CLL patients. The book is a fantastic resource and could be used by a range of professionals. Its main focus is on the laboratory diagnosis of B-CLL using basic methods as well as flow cytometry. Flow cytometry is further employed to demonstrate that ZAP-70 positive cells are more responsive to signals derived from their surounding environment, such as stromal cell-derived factor 1-alpha (SDF-1a).

Anbieter: Thalia AT
Stand: 04.12.2020
Zum Angebot
Married With Cancer
12,99 € *
zzgl. 3,00 € Versand

Eileen and Jimmy Newell had been married 24 years when Jimmy was diagnosed with Chronic Lymphocytic Cancer (CLL) during a routine physical exam. From the moment he called Eileen to deliver the news, she went from wife to wife/caregiver, a challenging role even with her training as a nurse. After several rounds of chemo over the course of seven years, Jimmy's cancer was declared as in remission, and things were looking up. Life was good-until Eileen was diagnosed with breast cancer ten years later, and suddenly, everything was turned on its head. Jimmy had to step into the role of caregiver, a role that life and a career in higher education had not prepared him for. In their book Married With Cancer, Eileen and Jimmy share how they coped as a couple through their cancer diagnoses and treatments, as patient and as caregiver. It hasn't been an easy journey, but they've had boundless love and laughter, some tears, and a few life lessons, which they share in this book to give hope and encouragement to their readers as they make their own journey toward survival.

Anbieter: Thalia AT
Stand: 04.12.2020
Zum Angebot